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Mexican Casserole Recipe

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Weeknights can be hectic, and that’s where this Mexican Casserole Recipe comes to the rescue. Perfect for busy parents, this family-friendly casserole is easy to prepare and loaded with bold, comforting flavors. Layers of soft tortillas, creamy refried beans, zesty salsa, and melty cheese create a dish that feels like a warm hug after a long day.

With simple ingredients and minimal prep, it’s an easy way to put a wholesome meal on the table that everyone will love.

Top image: A slice of layered Mexican casserole for Cinco de Mayo on a plate next to a full dish, with cutlery. Bottom image: Close-up of another slice showing layers of tortilla, cheese, and filling. Text: Enjoy this perfect Mexican Casserole for your Cinco de Mayo celebration!.

This Cinco de Mayo recipe is another Mexican-inspired family favorite! But better than that, Mexican Casserole is a super quick, kid-friendly recipe for busy moms!

This dish checks all the boxes, whether it’s a weeknight Mexican meal to bring the family together or a homemade casserole recipe to impress guests. Simple, satisfying, and flavor-packed, it’s sure to become a favorite.

Why You’ll Love Mexican Casserole Recipe

This Mexican Casserole Recipe is a go-to family favorite. It’s easy to make, with simple ingredients and minimal cleanup, perfect for busy schedules.

This layered tortilla dish is a winner whether you’re whipping up a quick dinner for busy moms or planning a cozy family meal.

Easy to Make

With just a handful of kitchen staples like refried beans, flour tortillas, salsa, and cheese, this recipe comes together in no time. The step-by-step layering makes it nearly foolproof, even for beginners.

Family-Friendly

Kids will love the cheesy, flavorful layers, while adults will appreciate its comforting, homemade taste. This dish truly brings everyone to the table for seconds!

Versatile

This baked Mexican recipe is incredibly flexible. If you prefer it spicier, swap in a medium or hot salsa. If you want to add protein, toss in cooked shredded chicken or ground beef. You can even mix in vegetables like diced bell peppers or corn for extra nutrition.

Quick Cleanup

Thanks to its one-pan prep, this hearty casserole requires fewer dishes to wash afterward. That means less time in the kitchen and more time to relax.

Serving Suggestions and Variations

Serve this casserole with chips and guacamole or a refreshing green salad for a complete meal. Top it with sour cream, fresh cilantro, or sliced jalapeños for added flair. You can also turn leftovers into a next-day treat by wrapping portions in tortillas for quick burritos.

This recipe is as practical as it is delicious, perfectly balancing bold flavors, convenience, and versatility. Once you try it, you’ll see why it’s a staple for various occasions!

Ingredients for Mexican Casserole Recipe

One of the best things about this Mexican Casserole Recipe is how simple the ingredients are. Every item plays a key role in building layers of flavor and texture, resulting in a mouthwatering dish perfect for any meal.

From savory bases to bold toppings, each component creates a comforting baked Mexican recipe everyone will love.

  • Flour Tortillas – The foundation of this layered tortilla dish provides structure and a soft, satisfying texture.
  • Refried Beans – Creamy and flavorful, adding richness and depth to each layer.
  • Salsa Packs every bite with zesty, bold flavors and a hint of spice. Depending on your preference, use mild, medium, or hot.
  • Shredded Cheese – Melts into ooey-gooey layers that bring the whole casserole together.
  • Cooked Protein (such as ground beef or chicken) – Optional but a great way to make the dish heartier and even more filling.
  • Vegetables (like diced bell peppers, onions, or corn) – Add a fresh and vibrant touch to balance the savory flavors.
  • Taco Seasoning – Elevates the dish with its perfect blend of Mexican-inspired spices.

Want exact measurements and a printable version of the recipe? Scroll to the recipe card below for all the necessary details to get started!

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Instructions to Make Mexican Casserole Recipe

Making this Mexican Casserole Recipe is as enjoyable as eating it! With a few simple steps, you’ll layer bold flavors and comforting textures into an irresistible dish. Follow along below, and don’t forget to have fun in the kitchen!

  1. Preheat the Oven – Start by preheating your oven to 375°F, ensuring your casserole bakes evenly.
  2. Prepare Your Protein – If you’re using ground beef or chicken, cook it in a skillet over medium heat until fully done. Add in taco seasoning for extra zing. This step adds a hearty layer to your casserole.
  3. Layer the Ingredients – Lightly grease a baking dish, then build your casserole by spreading a layer of refried beans on flour tortillas. Top with your cooked protein, salsa, a sprinkle of vegetables, and shredded cheese. Repeat the layers until you reach the top of the dish.
  4. Bake to Perfection – Cover the dish with foil and bake for 20 minutes. Remove the foil and bake for an additional 10 minutes, allowing the top layer of cheese to melt into golden, bubbly perfection.
  5. Rest Before Serving – Once baked, allow the casserole to sit for 5-10 minutes. This helps the layers set, making serving easier.
  6. Customize and Enjoy – Serve warm and offer toppings like sour cream, cilantro, or sliced jalapeños for added flair. Pair with sides like guacamole or a crisp green salad for the perfect meal.

Pro Tip: For an extra crispy finish, switch your oven to broil during the final minute or two of baking. Keep a close eye on it to avoid burning the cheese!

Slice of layered Mexican Casserole for Cinco de Mayo on a white plate, with the rest in the background. Text overlays read MEXICAN casserole and EASY recipe. Black-handled utensils are next to the plate, perfect for your festive celebration.

Mexican Casserole Tips and Tricks

Prep Ingredients in Advance – Chop veggies, cook your protein, and shred your cheese ahead of time to make assembly quick and stress-free.

Customize to Taste – Experiment with your family’s favorite ingredients. Add black beans, rice, or even hot sauce for extra spice.

Make it Ahead – This casserole is a great make-ahead dish. Assemble it the night before, refrigerate, and bake when ready.

Freeze for Later – This dish freezes beautifully! Wrap it tightly before baking; when you need a meal, thaw it overnight and pop it in the oven.

Keep Warm for Parties – Hosting a crowd? Prepare the casserole in a slow cooker to keep it warm and ready for serving.

Troubleshooting Mexican Casserole Recipe

Soggy Layers – Prevent soggy tortillas by using thicker ones or lightly toasting them before assembly. Avoid using too much salsa as it can add extra liquid.

Cheese That Doesn’t Melt – Ensure you’re using a cheese that melts well, like cheddar or Monterey jack. Pre-shredded cheese may take longer to melt due to anti-clumping agents.

Burnt Edges – Cover the dish with foil during the first stage of baking to prevent edges from overbaking. Remove the foil carefully for the final browning stage.

Dry Casserole – If your casserole seems dry, drizzle a bit of enchilada sauce or salsa between layers the next time you make it.

With these detailed steps, tips, and tricks, your baked Mexican recipe is sure to be a hit every time! Get ready to enjoy a dish loaded with flavor and perfect for any occasion.

Make sure you’re equipped with the best tools to prepare this Mexican Casserole Recipe with ease! Here are my top picks to help you cook, bake, and serve this layered tortilla dish like a pro:

  • Mixing Bowl Set – Perfect for combining all your ingredients effortlessly. Use it to prep vegetables, mix taco seasoning with ground meat, or even stir up a fresh side salad to complement your casserole. A good set of mixing bowls will keep your kitchen workflow smooth.
  • Baking Dish – The ideal tool for evenly baking this casserole to golden, bubbly perfection. Look for a sturdy, oven-safe dish that distributes heat well to ensure every layer bakes evenly and comes out deliciously.
  • Decorative Serving Bowl – Make mealtime feel extra special with a stylish serving bowl. Use it for sides like guacamole or chips to pair with your casserole, or showcase a vibrant topping selection like jalapeños, cilantro, and sour cream.

          

 

Customizing this Mexican Casserole Recipe for Every Diet

One of the best features of this Mexican Casserole Recipe is its flexibility. No matter your dietary preferences or restrictions, there’s a way to make this layered tortilla dish work for you without compromising on flavor or satisfaction. Here are some simple adjustments to customize this baked Mexican recipe for everyone at your table:

  • Gluten-Free – Swap regular flour tortillas for gluten-free ones. Many stores now carry delicious, sturdy options that hold up beautifully in baked recipes. Double-check your taco seasoning and other canned ingredients to ensure they’re also gluten-free.
  • Vegetarian – Skip the meat and load up on plant-based protein for a filling vegetarian option. Black beans, pinto beans, or even a hearty mix of lentils work wonderfully. You can also add in more veggies like zucchini, mushrooms, or spinach for extra texture and flavor.
  • Low-Carb – Replace the tortillas with thin slices of zucchini or eggplant as your layers. These veggie alternatives keep the dish comforting and satisfying while significantly reducing carbs. Another option is to use low-carb tortillas.
  • Vegan Option – Substitute dairy cheese with your favorite vegan cheese alternative. Opt for vegan-friendly refried beans and double-check your taco seasoning to ensure it’s free of animal products. You can still create rich, bold flavors with plant-based swaps!
  • Spice Level Adjustments – Whether you prefer mild or extra spicy, you can control the heat. Use mild salsa and leave out the jalapeños for a kid-friendly version, or kick it up with spicy salsa and a sprinkle of cayenne for those who crave extra heat.

Making small, thoughtful substitutions allows you to enjoy this casserole while accommodating different diets. This delicious dish truly works for every occasion and every eater!

A layered Mexican casserole with melted cheese on top, showcasing a slice revealing its filling on a white plate. Text overlay reads Mexican Casserole for Cinco de Mayo: Easy Comfort Food.

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Making a Meal Out of Mexican Casserole Recipe

This hearty Mexican Casserole Recipe is satisfying on its own, but with a few complementary dishes, you can turn it into a vibrant, well-rounded meal that’s sure to impress. Whether hosting a family dinner or a casual gathering, these pairings will complete your layered tortilla dish!

Sides

  • Mexican Street Corn (Elote) – The smoky, tangy flavors of grilled corn with crumbled cotija cheese and a squeeze of lime add a perfect touch of authenticity to your meal.
  • Crispy Tortilla Chips with Guacamole – A must-have pairing! The creamy guacamole adds freshness, while the chips provide the ideal crunch alongside your baked Mexican recipe.
  • Spanish Rice – A savory tomato-based rice dish that complements the casserole’s bold flavors and gives the meal a bit more substance.

Salads

  • Fresh Garden Salad with Lime-Cilantro Dressing – Add a bright and crisp component with a salad featuring lettuce, sliced cucumbers, cherry tomatoes, and a zesty dressing.
  • Black Bean and Corn Salad – A colorful mix of black beans, sweet corn, peppers, and red onion seasoned with lime and a hint of chili powder. It adds texture and a slight zing that balances the meal.

Drinks

  • Classic Margaritas (or Virgin Margaritas) – The tangy lime and touch of sweetness pair beautifully with the rich layers of the casserole.
  • Iced Tea with a Citrus Twist – A simple, refreshing option with a squeeze of lemon or orange makes for a great non-alcoholic choice.

Adding these sides, salads, and drinks transforms your casserole into a full-blown dining experience. Whether it’s for a festive gathering or a cozy night at home, this meal is bound to bring everyone to the table!

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Recipes with Beans

Beans are one of the most versatile kitchen ingredients, and their rich, savory flavor shines in many dishes. If you loved the hearty taste of beans in this Mexican Casserole Recipe, you’ll want to try these other flavorful ideas.

FAQs about Mexican Casserole Recipe

Got questions about making the perfect Mexican Casserole Recipe? Here are answers to some of the most common ones to help you confidently prepare this layered tortilla dish:

Yes! You can prepare the casserole up to a day in advance. Assemble all the layers, cover tightly, and store it in the fridge. When you’re ready to bake, simply pop it in the oven, adding a few extra minutes if it’s cold from the fridge.

Store any leftovers in an airtight container in the refrigerator for up to three days. When reheating, use the oven or microwave, and cover to keep the dish moist and prevent the cheese from drying out.

Absolutely! Ground turkey or shredded chicken are great alternatives to ground beef. For a vegetarian option, skip the meat and double up on beans or veggies like zucchini or mushrooms for a hearty filling.

To avoid soggy layers, lightly toast the tortillas before assembling the casserole. This adds a bit of texture and helps them hold up better in the baked dish.

The spice level is totally customizable. Use mild salsa or skip the jalapeños for a kid-friendly version, or crank up the heat with spicy salsa and a sprinkle of crushed red pepper for those who love a kick.

A slice of Mexican casserole with a golden crust graces a white plate, perfect for celebrating Cinco de Mayo. A fork lifts a bite, unveiling layers of tortillas, cheese, and flavor-packed ingredients. The text reads, Mexican Casserole full of flavor!.

Mexican Casserole Recipe Storage and Reheating Tips

Leftovers from this Mexican Casserole Recipe are just as delicious as the freshly baked dish, and with proper storage and reheating, you can enjoy it for days to come. Here are some tips to keep your layered tortilla dish tasting amazing:

Storage Tips

  • Refrigerate Properly – Transfer any leftovers to an airtight container and store them in the fridge for up to three days. This helps maintain the flavors and prevents the dish from drying out.
  • Freezing Option – If you want to save some for later, freeze individual portions in freezer-safe containers or tightly wrapped aluminum foil. The casserole will stay fresh for up to three months in the freezer.

Reheating Tips

  • Microwave – For quick reheating, microwave individual servings on a microwave-safe plate, covered with a paper towel to prevent splatter. Heat in 30-second increments to avoid overcooking.
  • Oven – Reheat larger portions in the oven at 350°F. Cover with foil to keep the casserole moist and heat for 15-20 minutes, or until warmed and bubbly.
  • Skillet Quick Fix – Reheat smaller portions in a skillet over medium heat. Add a splash of water or broth if needed to refresh the layers.

Creative Leftover Ideas

  • Topping for Nachos – Use the casserole to top tortilla chips, then sprinkle with extra cheese and bake in the oven for loaded nachos that everyone will love.
  • Stuffed Baked Potatoes – Scoop out baked potato halves and stuff them with warmed casserole for a hearty twist on dinner.
  • Filling for Quesadillas – Spread leftover casserole between two tortillas or fold it into one, then grill until crispy on both sides for lunch or a snack.

Storing and reheating this baked Mexican recipe is easy, and with these innovative ideas, you can reinvent your leftovers into fresh and exciting meals!

A slice of layered taco pie, reminiscent of a Mexican casserole, sits on a white plate. Filled with savory meat and topped with melted cheese, its the perfect dish for Cinco de Mayo. A turquoise napkin peeks in from the corner, hinting at another pie in the background.

Mexican Casserole for Cinco de Mayo

Kelli Miller
Mexican Casserole is a super quick, kid-friendly, Cinco de Mayo recipe for busy moms!
5 from 3 votes
Prep Time 5 minutes
Cook Time 20 minutes
Total Time 25 minutes
Course Main Dish
Cuisine Mexican
Servings 8
Calories 447 kcal

Ingredients
  

  • 1 16 ounce can refried beans
  • ¾ onion diced
  • 5 10 inch flour tortillas
  • 1 Cup(s) salsa
  • 2 Cup(s) shredded Cheddar or Colby Jack cheese

Instructions
 

  • Preheat oven to 375 degrees F Spray a 9-inch pie pan with non-stick cooking spray.

  • In a saucepan, cook refried beans and onions on medium-high heat for about 5 minutes.

  • Place one tortilla in the bottom of the greased pan. Spread about 1/3 cup of the bean mixture over it. Layer a few tablespoons of salsa over this. Then, place another tortilla over the salsa, and add more of the bean mixture. Follow the beans with a big handful of cheese, spreading evenly. repeat layers, spreading the ingredients evenly over the tortillas.

  • Bake until the cheese is melted, approximately 15 to 20 minutes.

Nutrition

Serving: 1gCalories: 447kcalCarbohydrates: 72gProtein: 13gFat: 11gSaturated Fat: 4gPolyunsaturated Fat: 3gMonounsaturated Fat: 2gCholesterol: 0.2mgSodium: 1315mgPotassium: 180mgFiber: 7gSugar: 7gVitamin A: 53IUVitamin C: 1mgCalcium: 216mgIron: 5mg
Keyword Mexican casserole recipe
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More Recipes Like Mexican Casserole Recipe

Love the flavors and simplicity of this Mexican Casserole Recipe? Here are a few other dishes that capture that same hearty, satisfying appeal. Each one offers bold flavors, easy preparation, and plenty of options to customize:

  • Chicken Enchilada Casserole – A baked Mexican recipe that layers shredded chicken, enchilada sauce, tortillas, and cheese for the ultimate comfort food. It’s a perfect dish to make and freeze for quick weeknight meals.
  • Taco Lasagna – Think of a layered tortilla dish with a fun Tex-Mex twist! Ground beef, refried beans, tortillas, salsa, and cheese come together to form a lasagna-style creation that’s always a hit at family dinners.
  • Beef and Bean Burrito Bake – Roll up seasoned ground beef and beans into flour tortillas, place them in a baking dish, and smother with cheese and enchilada sauce. This dish has all the flavor of burritos without the hassle of wrapping each one individually at the table.
  • Tamale Pie – A savory, layered dish featuring a flavorful ground beef or pork base topped with cornbread batter. The cornbread bakes to golden perfection, soaking up all the rich sauce underneath for an irresistible meal.

These recipes are ideal for anyone who loves a hearty, layered tortilla dish or is looking for variations on a classic baked Mexican recipe. Give them a try and discover new family favorites!

A slice of layered taco pie, reminiscent of a Mexican casserole, sits on a white plate. Filled with savory meat and topped with melted cheese, its the perfect dish for Cinco de Mayo. A turquoise napkin peeks in from the corner, hinting at another pie in the background.

This Mexican Casserole Recipe is everything you want in a comforting, family-friendly meal. It’s easy to make, packed with bold flavors, and endlessly versatile. Whether you’re serving it for a weeknight dinner or a casual get-together, it’s sure to be a crowd-pleaser.

I’d love to hear how your version turned out! Did you try any creative twists or add your own special touch? Comment below to share your experience or any tips you think others would enjoy.

Don’t forget to save this recipe for the next time you’re craving something hearty and delicious. And if you loved this dish, explore more of our family-friendly favorites for meal ideas that everyone around the table will adore.

Happy cooking, and enjoy every cheesy, flavorful bite!

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6 Comments

  1. I love Mexican food. This is a great recipe to have at gatherings just in case someone is vegetarian. It will do double duty because those that aren’t will love it also. Thanks for sharing.

    Lisa

  2. I can eat Mexican food any day of the week! This recipe sounds perfect for a busy night and I need a quick meal.

  3. 5 stars
    Thanks for sharing this delish dish in the weekly Bowdabra Crafty Showcase.

    The new showcase opens up Friday midnight and runs through Thursday noon. We hope that you share more of your crafty creations.

    http://bowdabrablog.com/

    susie @Bowdabra

  4. 5 stars
    Thank you so much for sharing this awesome recipe with Full Plate Thursday. Hope you have a very special Mothers Day Weekend and come back soon!
    Miz Helen

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